这一季对应原著小说第七部和第八部，主人公乌特雷德尝试夺回贝班堡未果，后又卷入麦西亚君位之争，并再次面对丹麦人入侵。
The doctors from Grey Sloan Memorial Hospital spring into action to save the lives of two girls with a powerful story. Meanwhile, Meredith tries to cope with the fact that Amelia is now living with her and Jackson prepares for April's return back to Seattle.
该剧设定自一个平行世界，苏联先于美国完成人类登月，在那个世界中苏美航天竞赛从未停止，并各自在月球上建立了永久基地。
