一辆休旅车冲下悬崖，司机当场死亡。死者涉及一桩枪案，但赃物却不见踪影。法国警官维威耶和瑞士警探梅耶再次联手破解谜团。
John Wood left the pieces of a broken civilisation behind, to go back to his roots in the woodland, after a virus pandemic struck the world. Residing in a simple cabin, he only wants peace and to live in harmony with nature. Coming from a long line of timber men, he joined the army and served as a soldier for many years. Rebelling against his superiors for killing civilians under martial law. John feels he got his own wife killed when saving hundreds of innocent civilians from certain death. His wife executed point blank as retribution for John's disobedience and supposed heroic acts. Now, a young woman named Maria Johnson has escaped a pandemic research lab. She's been part of experiments to find a cure for the still raging virus. Carrying the potential cure in her blood, she is hunted by profiteers and mercenaries who knows her secret. Coming upon John's cabin in the woods, Maria is instinctively taken into shelter by John. He wants her to recover fast and leave, but by learning her...
阿华（刘德华 饰）一直想当一名好警察，正当他得到了好机会正想大展拳脚的时候，他被调至的小组意志十分消沉，完全没有工作的干劲。他们的队伍常常受到另一队由张扬（张耀扬 饰）的出色人马藐视。阿华十分不满扬的作风，更在一次行动中与之发生冲突。 阿华的母亲（林建明 饰）召回了家中，因为阿华的女友阿兰（张曼玉 饰）受父亲（秦沛 饰）所逼要嫁给一个与她完全没有感情的有钱人，阿兰的父亲更是阿华的师傅，情与义之间不知如何抉择。令阿华更加烦恼的是，自己的母亲竟然与自己的同事秋（黄秋生 饰）发生了感情。 回到警察局后，一群匪徒企图闯进入拯救自己的同党，但阿华成功擒拿匪徒的功劳竟然被张扬设计夺走。忍无可忍的阿华决定与张扬在跆拳道赛中一决胜负。
生物科技公司研究员卢克·李（吴尊 饰）深入一座古墓随即失去音讯，剧毒生物学博士嘉·李（李冰冰 饰）得知弟弟卢克失踪的消息，随即与医药集团总裁梅森·伯罗斯（凯尔希·格兰莫 饰）组建一支专业的搜救队，在救援队长杰克·雷德利（凯南·鲁兹饰）的带领下，一行人前往卢克·李失踪的地点搜寻，却意外闯入神秘地下世界，一段意想不到冒险之旅就此展开……
