本剧继续通过荧幕呈现James Herriot创作的故事，观众将回到Darrowby，重新加入不拘一格、备受喜爱的Skeldale大家庭，以及1940年代生活在约克郡山谷的农场主、动物和乡亲们。
Jenna是一名公立学校教师，被指控与一名学生酒后发生了性关系，她的生活随之开始瓦解。由于没有当晚的记忆，Jenna唯一的救赎希望，是揭开自己过去难以启齿的一件事，这件事如今又再次困扰着她。 Barunka O’Shaughnessy 和Mike Benson共同创作，前者担任领头编剧，Dominic Leclerc担任导演。
本剧讲述主角Alex从小在英国长大，他父亲是俄国流亡而来的黑手党，主角一直试图脱离自己那犯罪过去，建立自己的合法事务及与女友一同生活。但当他的家族历史威胁到他们时，Alex被拉回那犯罪世界，并为了保护所爱而对抗起自己的价值观。
构思源自同名纪录片，这部医务剧以全美最忙碌，名声也最不堪的洛杉矶县医院的急症室为故事背景。一群医术精湛的医生尽管受制于落后的制度，但他们仍为理想、为病人努力奋斗。
Mrs. Brown's Boys became a runaway success upon its initial broadcast. Every episode aired won its timeslot for RTÉ, with an average viewership of 753,500 in January, 2011. One episode's rating beat that of RTÉ's own ratings giant The Late Late Show, with 856,000 viewers tuning in to watch. However, critics disliked the show. "The whole thing is entirely predicated on viewers finding a man dressed as a foul-mouthed elderly woman intrinsically funny," noted Bernice Harrison in the Irish Times. "If you do, you’re away in a hack (and the viewing figures are astronomical), but if you don’t, and you think that died out with Les Dawson and Dick Emery, then it’s a long half-hour." The Irish Independent said that Mrs Brown's Boys was the type of TV programme that "that makes you vaguely embarrassed to be Irish". The Daily Telegraph's Sam Richards noted that show's comedy has a "rudimentary nature", consisting of "an old-fashioned blend of silly voices and slapstick, played out in front of a live studio audience who collapse into giggles at the mere mention of the word “willy”.
