讲述退役特种兵程凯，为寻找失踪的医疗队员妻子肖玲，孤身闯入恐怖势力猖獗的沙查尔地区。他潜入核心据点塔林，与盘踞此地的雇佣兵展开较量。期间受被掳女孩米拉的关键帮助，二人躲避追杀，历经重重艰险，最终成功冲破封锁，将米拉救出雇佣兵的魔掌的故事。
Mike Locken is one of the principal members of a group of freelance spies. A significant portion of their work is for the C.I.A. and while on a case for them, one of his friends turns on him and shoots him in the elbow and knee. His assignment, to protect someone, goes down in flames. He is nearly crippled, but with braces is able to again become mobile. For revenge as much as anything else, Mike goes after his ex-friend.
魏佳欢生日这天，父亲魏成功陪她登上环海游艇，然而一场突如其来的海难打破了一切，整艘游艇侧翻，众人纷纷落水。魏成功自哭喊声中醒来，发现自己身处一荒岛，目睹魏佳欢被一巨蛇叼走，于是随众人深入丛林，踏上营救之路。在这片与世隔绝的丛林里，无数怪异的史前生物暗藏其中，营救女儿的遥遥之途布满杀机。另一边，魏佳欢等人在蛇穴中醒来，在失去规则的封闭环境中，幸存者的人性也承受着巨大考验…
